中文摘要：

为探讨高蛋白食物和繁殖对布氏田鼠食物摄入和产热等特征的效应,将成年雌性布氏田鼠分为非繁殖对照食物组、非繁殖高蛋白组、繁殖对照食物组和繁殖高蛋白组。对照食物蛋白含量为17.7%,高蛋白食物的蛋白含量为36.6%。实验过程中测定动物的体重、食物摄入量、静止代谢率（RMR）、身体成分、内脏器官重量、褐色脂肪组织（BAT）解偶联蛋白1（UCP1）含量、血清瘦素和催乳素水平等。结果发现：高蛋白食物明显抑制布氏田鼠的体重,但动物在妊娠期和哺乳期,这种抑制作用消失。高蛋白食物明显抑制非繁殖组动物的干物质摄入、摄入能和消化能,但对哺乳期动物没有影响。高蛋白食物提高了非繁殖期和繁殖期动物的消化率,降低了血清瘦素浓度,但仅提高了繁殖期动物肾脏的重量,而降低了盲肠的重量。RMR、UCP1含量和血清催乳素浓度等则不受高蛋白食物的影响。繁殖期动物的体重、能量摄入、RMR和血清催乳素浓度等均高于非繁殖动物。这些结果表明,食物蛋白含量可影响布氏田鼠的能量代谢和产热特征等,且在繁殖期和非繁殖期有不同的反应方式。

英文摘要：

The present study was designed to explore the effects of high protein diet and reproduction on food intake and thermogenesis in Brandt＇ s voles （Lasiopodomys brandtii）. The adult female Brandt＇ s voles were divided into four groups, non-reproduction and control diet （NCon, 17.7% of protein）, non-reproduction and high protein diet （NHP, 36. 6% of protein）, reproduction and control diet （RCon）, and reproduction and high protein diet （RHP）. Body mass, body com- position, organ mass, food intake, resting metabolic rate （RMR）, uncoupling protein 1 （UCP1） content in brown adipose tissue （BAT） , and serum leptin and prolactin levels were measured. Body mass was decreased in voles fed high protein diet, but this effect was disappeared during pregnancy and lactation. Food intake, gross and digestible energy intake were decreased in non-reproductive voles fed high protein diet, but not during lactation in reproductive voles fed high protein di- et. Digestibility was increased and serum leptin was decreased in both non-reproductive and reproductive voles fed high protein diet. The kidney mass was increased and caecum mass was decreased in reproductive voles fed high protein diet. High protein diet had no effects on RMR, UCP1 content and serum prolactin levels in both non-reproductive and reproduc- tive voles. The body mass, energy intake, RMR and serum prolactin were increased in reproductive voles compared with non-reproductive ones. Our results suggest that food quality can affect the energy metabolism in Brandt＇ s voles, and voles with different reproductive status showed different responses.