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VE的微乳化研究
  • ISSN号:1003-5788
  • 期刊名称:《食品与机械》
  • 时间:0
  • 分类:TQ649.69[化学工程—精细化工]
  • 作者机构:[1]江南大学化学与材料工程学院,江苏无锡214036, [2]江苏省原子医学研究所,江苏无锡214063
  • 相关基金:国家自然科学基金项目(项目编号:20473034);江南大学“太湖学者”(2003)专项基金、教育部重点实验室开放课题(项目编号:KLIB-KF200504)
中文摘要:

以Tween80为表面活性剂,正丁醇为助表面活性剂,通过绘制拟三元相图对食品级VE的O/W型微乳液配方和工艺进行了研究。结果表明:最佳条件为:在35℃下,Tween80:正丁醇=1:1;VE:SAA:水为1:99:900。温度对微乳区域影响的考察发现随温度升高微乳区面积减小;通过分析电导率随组分变化的曲线划分出不同微乳类型区;用动态光散射法测定VE微乳液粒径大小一个月内的变化情况,表明VE微乳液稳定且平均粒径小于10nm;以正己烷为透析液,在25℃下,利用渗析一紫外分光光度法测定样本的释药率,显示48h后VE的包封率高达83.7%,具有明显的缓释作用。

英文摘要:

The formulation and process of food-grade vitamin E microemulsion were studied by using Tween80 as surfactant, n-Butylalcohol as cosurfactant. Based on the test results, the optimal condition was as follows: Tween80 : n-Butylalcohol = 1 : 1 , the proportion of vitamin E : SAA : water was 1:99 :900 at 35℃. Influence of temperature on the microemulsion region was determined with ternary diagrams. With the temperature increasing, the area of microcmulsion decreased. The O/W, W/O and B. C. regions were divided by conductance method. The changes of diameter of microemulsion in a month were measured by Dynamic Light Scattering in O/W region and the results showed that it was stable and the particle radius was less than 10 nm. Release rate of vitamin E against hexane was measured with dialysis-Uhraviolet Spectrophotometer. The resuhs revealed that the vitamin E envelopment was reached at 83.7% after 48 h, bearing remarkable release efficiency.

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期刊信息
  • 《食品与机械》
  • 北大核心期刊(2011版)
  • 主管单位:湖南省教育厅
  • 主办单位:长沙理工大学
  • 主编:黄寿恩
  • 地址:长沙市万家丽南路二段960号
  • 邮编:410004
  • 邮箱:foodmm@21cn.com
  • 电话:0731-85258200 85258201
  • 国际标准刊号:ISSN:1003-5788
  • 国内统一刊号:ISSN:43-1183/TS
  • 邮发代号:42-83
  • 获奖情况:
  • 一级期刊
  • 国内外数据库收录:
  • 中国中国科技核心期刊,中国北大核心期刊(2004版),中国北大核心期刊(2008版),中国北大核心期刊(2011版),中国北大核心期刊(2014版)
  • 被引量:20609