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An effective amperometric biosensor based on graphene modified gold nanowire arrays for glucose detection
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  • 分类:O657.1[理学—分析化学;理学—化学] TP212.3[自动化与计算机技术—控制科学与工程;自动化与计算机技术—检测技术与自动化装置]
  • 作者机构:[1]Laboratory of Functional Nanomaterials and Devices, School of Materials Science and Engineering, Hefei University of Technology, Hefei 230009, China, [2]Key Laboratory of Advanced Functional Materials and Devices of Anhui Province, Hefei 230009, China
  • 相关基金:This work was supported by the National Nat- ural Science Foundation of China (91023030, 51072044, 51102071, 51172059, and 51272063) and the International Scientific and Tech- nological Cooperation Project of Anhui Province ( 10080703017).
中文摘要:

一个新奇葡萄糖生物传感器基于 graphene nanosheets (GN ) 修改了金 nanowire 数组(AuNWAs ) 电极被构造。高度订的金 nanowire 数组被直接电极淀积在阳极的铝氧化物模板准备。GN 通过包含石墨氧化,脱落,和化学减小的一条公共线路被综合。扫描电子显微镜和高分辨率的传播电子显微镜的地排放被采用描绘同样准备的 AuNWAs 和 GN。葡萄糖 oxidase 在 GNs-AuNWAs 的表面上被使不能调动经由一个 cross-linking 方法的修改电极。周期的 voltammetry 结果证明 GNs-AuNWAs-based 葡萄糖生物传感器举办高催化作用活动到氢过氧化物(H < 潜水艇 class= “ a-plus-plus ” > 2 O < 潜水艇 class= “ a-plus-plus ” > 2 ) 比仅仅与 GN 或 AuNWAs 修改的那些。而且,安培计的反应被采用由于它的简洁,高选择,和相对低费用检测葡萄糖集中。葡萄糖生物传感器与 40.25 的高敏感基于 GNs-AuNWAs 显示出优秀性能 ? 一 ? 厘米 < 啜 class= “ a-plus-plus ” > 2 ?(mmol/L) 1 , 0.02 的低察觉限制 ? mmol/L,和从 0.02 ~ 3 的一个线性范围 ? mmol/L。

英文摘要:

A novel glucose biosensor based on graphene nanosheets (GNs) modified gold nanowire arrays (AuN- WAs) electrode was constructed. Highly ordered gold nanowire arrays were prepared by direct electrodeposition in anodic aluminum oxide templates. GNs were synthe- sized through a public route involving graphite oxidation, exfoliation, and chemical reduction. Field emission scan- ning electron microscope and high-resolution transmission electron microscope were employed to characterize the as- prepared AuNWAs and GNs. Glucose oxidase was immobilized on the surface of GNs-AuNWAs modified electrode via a cross-linking method. The cyclic voltam- metry results showed that the GNs-AuNWAs-based glu- cose biosensors have high catalysis activity to hydrogen peroxide (H2O2) than those modified with GNs or AuN- WAs only. Furthermore, amperometric response was employed to detect glucose concentration owing to its simplicity, high selectivity, and relative low cost. Glucose biosensors based on GNs-AuNWAs showed excellent performance with high sen- sitivity of 40.25 μA cm^-2 (mmol/L)^-1, low detection limit of 0.02 mmol/L, and a linear range from 0.02 to 3 mmol/L.

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