哮喘和慢性阻塞性肺疾病(COPD)是两种不同的疾病,两者具有不同的特征,但有时难以将两者区分,尤其当哮喘患者病情加重出现类似COPD症状,而具有吸烟史的COPD患者表现出哮喘特征时,现将同时具备哮喘和COPD临床特征的疾病状态定为哮喘-慢性阻塞性肺疾病重叠综合征(ACOS)。本文从流行病学、病因、病理生理学特征、急性加重情况、生活质量和医疗费用、诊断标准以及治疗等方面,对ACOS近年的临床研究进展做一总结。
Asthma and chronic obstructive pulmonary disease( COPD) are two different diseases with different characteristics,but sometimes it is difficult to distinguish them,especially when asthma patients show COPD- like symptoms and COPD patients with history of smoking show asthma characteristics. It is now stated as asthma and chronic obstructive pulmonary disease overlap syndrome( ACOS). This article aims to sum up the progress of the recent clinical studies of ACOS from the aspects of epidemiology,etiology,pathology and physiology characteristics,acute aggravation,quality of life and health care costs,diagnostic criteria and treatment.