酚酸是一类天然抗氧化活性成分,酯化修饰不仅可以提高酚酸类化合物的脂溶性,而且可以有效改善其生物活性。本文综述了酚酸酯的化学和酶催化合成方法及其在化学和细胞两个方面的抗氧化活性研究进展,探讨了现有的酚酸酯合成方法存在的问题和解决方案,以及不同抗氧化活性评价方法的特点,并展望其未来发展方向,为高效脂溶性抗氧化剂的开发及其在食品、药品、化妆品等领域的广泛应用提供参考。
Phenolic acids are natural antioxidant ingredients. Esterification improves the lipophilicity of phenolic compounds,and also improves their biological activities. This paper reviewed the research progress of chemical and enzymatic synthesis methods of lipophilic phenolic acid esters. Their antioxidant activity was also included.Problems on synthesis method and antioxidant activity evaluation method were discussed with future application. It was to provide supports for wider use of lipophilic phenolic acid esters in food,pharmaceuticals,cosmetics and other fields as novel lipophilic antioxidants.