中文摘要：

目的观察五子衍宗丸加味治疗肾虚型男性不育患者的临床疗效,探索提高肾虚型男性不育患者精液质量的治疗方法。方法选择肾虚型男性不育患者50例,均给予五子衍宗丸加味治疗,1个月为1个疗程,3个疗程为1个治疗周期。治疗1个周期后统计疗效,比较治疗后精液液化时间、精液量、精子密度、精子总数、精子活率、A级精子比率、A＋B级精子比率、血清睾酮水平。结果治疗1个周期后,治愈率为30%,总有效率为94%。治疗前精液液化时间、精液量、精子密度、精子总数、精子活率、A级精子比率、A＋B级精子比率、血清睾酮水平分别为（48.2±16.49）min、（2.80±1.03）m L、（48.25±38.76）×10~6m L~（-1）、（135.20±121.40）×10~6m L~（-1）、（35.74±20.54）%、（15.10±12.95）%、（28.40±17.36）%和（3.35±0.82）nmol/L,治疗后分别为（46.46±18.57）min、（3.24±0.97）m L、（59.15±47.95）×10~6m L~（-1）、（174.32±143.85）×10~6m L~（-1）、（49.92±21.56）%、（23.50±14.77）%、（40.47±19.29）%和（4.93±1.03）nmol/L,治疗后精液量、精子密度、精子总数、精子活率、A级精子比率、A＋B级精子比率、血清睾酮水平均较治疗前显著改善（P均〈0.05）。结论五子衍宗丸加味可明显改善不育患者精液质量,提高血清睾丸酮水平。

英文摘要：

Objective It is to olDserve the clinical curative effect of Wuzi Yanzong Pill （WZYZP） in treating male infertil-ity patients with kidney deficiency, and explore the method of improve the semen quality of male infertility patients with kidney deficiency. Methods 50 cases of male infertility patients with kidney deficiency were selected, and were treated with WZYZP, one month as a course of treatment, three course is a treatment cycle. The clinical curative effect was statistically analyzed af-ter a treatment cycle, and the changes of semen liquefaction time, semen volume, sperm density, total sperm count, sperm activity rate, grade A sperm ratio, grade A ＋ B sperm ratio, and serum testosterone levels were observed and compared before and after treatment. Results After a treatment cycle, the recovery rate was 3 0%, the total effective rate was 94% ？ The semen liquefaction time,semen volume,sperm density, total sperm count, sperm activity rate, grade A sperm ratio, grade A ＋ B sperm ratio,and serum testosterone level was （48.20 ± 16. 49） min, （2. 80 ±1.03） mL, （48. 25 ± 38. 76） x l〇 6 mL 1, （135.20 ± 121.40） x 106 mL＂1 , （35. 74 ± 20. 5 4）% , （15. 10 ± 12. 95） % , （28. 40 ± 17. 36） % , and （3. 35 ± 0. 82） nmol/L respectively before treatment,and was （46.46 土 18. 57） min, （3 .2 4 ± 0 .9 7 ） mL, （59？ 15 土 47？ 95） x 106 mL＂1 , （174.32 ± 143.85） x 106 mL-1 , （4 9 .9 2 ± 21.5 6 ） % , （23. 5 ± 14.7 7 ）% , （40.47 ± 19.2 9 ）% , and （4 .9 3 ± 1.03） nmol/ L respectively after treatment. The semen volume, sperm density, total sperm count, sperm activity rate, grade A sperm ratio, grade A ＋ B sperm ratio, and serum testosterone levels after treatment were significantly improved than l 3 efore （all P 〈0. 0 5 ） . Conclusion WZYZP can significantly improve the semen quality of male infertile patients, and increase the serum testosterone level.