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中文摘要：
婴儿痉挛症是一种独特的,且具有年龄特异性的婴儿早期癫痫综合征.具有发病年龄早、发作形式特殊、进行性智力减退、脑电图呈高峰节律紊乱等特征.其病因复杂、多样,发病机制迄今尚未明确.虽然目前国内外对于其治疗相关的指南、共识小断推陈出新,但该病治疗方面仍存在困难,遗留智能缺陷等后遗症.现通过对近年来的文献复习,介绍婴儿痉挛症最近的治疗进展情况.重点介绍皮质激素和氨己烯酸的使用,以及婴儿痉挛征的质量控制指标。
英文摘要：
Infantile spasms constitutes an unique,age-specific epilepsy syndrome of early infancy characterized by epileptic spasms often accompanied by neurodevelopmental regression and an electroencephalograph finding of hypsarrhythmia.For the complex and various etiologies,the pathogenesis remains unclear.Although the relevant guidelines and consensuses are being updated all the time,but proven therapies are still limited because of efficacy,tolerability,at times even availability.In this paper,the current findings regarding up-to-date advances in the treatment of infant spasms were reviewed,especially in use of the corticosteroid and vigabatrin as well as the quality-of-care indicators for infantile spasms.
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