中文摘要：

以聚偏氟乙烯（PVDF）微孔滤膜为基膜，S-布洛芬为模板分子，丙烯酰胺为功能单体，乙二醇二甲基丙烯酸酯为交联剂，采用热引发表面自由基聚合的方式制备了S-布洛芬印迹复合膜，并研究了其对布洛芬外消旋体的吸附及拆分性能。结果表明，该印迹膜对S-布洛芬具有一定的特异性吸附能力，当布洛芬异构体浓度在0．1～0．5mmol／L范围内逐渐增大时，吸附量也逐渐增大，吸附选择性因子则由1．68降至1．14；该膜对布洛芬异构体具有一定的拆分能力，渗透实验进行7h，膜对R-布洛芬及S-布洛芬的渗透量分别为0．378和0．313μmol／（cm^2·h），分离因子可达到1．21。

英文摘要：

A composite membrane （MIM） molecularly imprinted with S-ibuprofen has been prepared by using a po- ly（vinylidene fluoride） （PVDF） membrane as supporting membrane, S-ibuprofen as template, acrylamide （AM） as functional monomer, and ethylene glycol dimethacrylate （EGDMA） as cross-linking agent via free radical poly- merization. The adsorption and chiral resolution properties of the MIM for racemic ibuprofen were evaluated. The results indicated that the prepared MIM had a certain specific adsorption ability for S-ibuprofen. The adsorption a- mount increased with increasing ibuprofen concentration from 0. 1 to 0.5 mmol/L, but the adsorption selectivity fac- tor decreased from 1.68 to 1.14. The resolution ability of the MIM was evaluated by permeability testing. The per- meation amounts of R-ibuprofen and S-ibuprofen were 0. 378 and 0.313 μmol/（cm2· h） , respectively, and the sep- aration factor could reach I. 21.