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Analysis of Environmental Endocrine Disrupting Activities in Wastewater Treatment Plant Effluents Using Recombinant Yeast Assays Incorporated with Exogenous Metabolic Activation System
  • ISSN号:0250-3301
  • 期刊名称:《环境科学》
  • 时间:0
  • 分类:X505[环境科学与工程—环境工程] X503[环境科学与工程—环境工程]
  • 作者机构:[1]Engineering Research Center of Groundwater Pollution Control and Remediation, Ministry of Education, College of Water Sciences, Beijing Normal University, Beijing 100875, China, [2]State Key Laboratory of Environmental Aquatic Chemistry, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China, [3]State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, Guangdong, China
  • 相关基金:supported by the National Natural Science Foundation of China (No. 20737003); the Important Research Direction of Chinese Academy of Sciences (KZCX2‐YW‐Q02‐05)
中文摘要:

目的将在废水测量内分泌的破坏化学药品(EDC ) 并且在市政的废水处理工厂(WWTP ) 评估 EDC 移动效率。方法一组在里面与外长的新陈代谢的激活系统合并的 vitro recombinant 酵母生物鉴定(老鼠肝准备, S9 混合)被进行估计雌激素受体(嗯),雄激素受体( AR ),孕酮受体( PR ),并且自河的甲状腺受体( TR ) ant/agonistic 活动从 Datansha 收集了 WWTP 。结果间接雌激素, anti-androgenic, anti-progesteronic,和 anti-thyroidic 活动被观察在流入。EDC 的移动效率超过 74% ,建议现在的废水处理过程足够好移开大多数这些间接内分泌的破坏化学药品。结论进测试系统的外长的新陈代谢的能力的加入为间接效果在上的学习是有效的嗯, AR, PR,和 TR。

英文摘要:

Objective To measure the endocrine disrupting chemicals (EDCs) in wastewater and evaluate the EDCs removal efficiencies in the municipal wastewater treatment plants (WWTP). Methods A battery of in vitro recombinant yeast bioassays incorporated with exogenous metabolic activation system (rat liver preparation, S9 mix) was conducted to assess the estrogen receptor (ER), androgen receptor (AR), progesterone receptor (PR), and thyroid receptor (TR) ant/agonistic activities of effluents collected from Datansha WWTP. Results The indirect estrogenic, anti‐androgenic, anti‐progesteronic, and anti‐thyroidic activities were observed in the influent. The removal efficiencies of EDCs were above 74%, suggesting that the present wastewater treatment processes were good enough to remove most of these indirect endocrine disrupting chemicals. Conclusion The incorporation of exogenous metabolic capacity into the test system was valid for the study of indirect effects on ER, AR, PR, and TR.

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期刊信息
  • 《环境科学》
  • 中国科技核心期刊
  • 主管单位:中国科学院
  • 主办单位:中国科学院生态环境研究中心
  • 主编:赵进才
  • 地址:北京市2871信箱(海淀区双清路18号)
  • 邮编:100085
  • 邮箱:hjkx@rcees.ac.cn
  • 电话:010-62941102 62849343
  • 国际标准刊号:ISSN:0250-3301
  • 国内统一刊号:ISSN:11-1895/X
  • 邮发代号:2-821
  • 获奖情况:
  • 在全国第一届和第二届优秀科技期刊评比中分别荣获...,二次荣获中国科学院优秀期刊评比一等奖,荣获中国期刊方阵双奖期刊荣誉
  • 国内外数据库收录:
  • 俄罗斯文摘杂志,美国化学文摘(网络版),荷兰文摘与引文数据库,美国工程索引,美国生物医学检索系统,美国剑桥科学文摘,美国生物科学数据库,英国动物学记录,日本日本科学技术振兴机构数据库,中国中国科技核心期刊,中国北大核心期刊(2004版),中国北大核心期刊(2008版),中国北大核心期刊(2011版),中国北大核心期刊(2014版),中国北大核心期刊(2000版)
  • 被引量:69962