目的将在废水测量内分泌的破坏化学药品(EDC ) 并且在市政的废水处理工厂(WWTP ) 评估 EDC 移动效率。方法一组在里面与外长的新陈代谢的激活系统合并的 vitro recombinant 酵母生物鉴定(老鼠肝准备, S9 混合)被进行估计雌激素受体(嗯),雄激素受体( AR ),孕酮受体( PR ),并且自河的甲状腺受体( TR ) ant/agonistic 活动从 Datansha 收集了 WWTP 。结果间接雌激素, anti-androgenic, anti-progesteronic,和 anti-thyroidic 活动被观察在流入。EDC 的移动效率超过 74% ,建议现在的废水处理过程足够好移开大多数这些间接内分泌的破坏化学药品。结论进测试系统的外长的新陈代谢的能力的加入为间接效果在上的学习是有效的嗯, AR, PR,和 TR。
Objective To measure the endocrine disrupting chemicals (EDCs) in wastewater and evaluate the EDCs removal efficiencies in the municipal wastewater treatment plants (WWTP). Methods A battery of in vitro recombinant yeast bioassays incorporated with exogenous metabolic activation system (rat liver preparation, S9 mix) was conducted to assess the estrogen receptor (ER), androgen receptor (AR), progesterone receptor (PR), and thyroid receptor (TR) ant/agonistic activities of effluents collected from Datansha WWTP. Results The indirect estrogenic, anti‐androgenic, anti‐progesteronic, and anti‐thyroidic activities were observed in the influent. The removal efficiencies of EDCs were above 74%, suggesting that the present wastewater treatment processes were good enough to remove most of these indirect endocrine disrupting chemicals. Conclusion The incorporation of exogenous metabolic capacity into the test system was valid for the study of indirect effects on ER, AR, PR, and TR.