中文摘要：

嗅觉的 ensheathing 房间(OEC ) 是有 axonal 的 glial 房间的一种唯一的类型支持生长的性质。OEC 移植作为 axonal 损害和 demyelinating 疾病的有希望的试验性的治疗出现了。然而， OEC 的一些基本细胞的性质仍然保持不清楚。在这研究，我们发现不同 OEC 候补选手人口基于单个孤立的房间的微速摄影的成像展出了不同迁移的性质，可能由于他们的不同细胞骨架组织。而且， OEC 潜水艇人口在单个房间的迁居试金显示了不同吸引人的迁移的回答到 lysophosphatidic 酸(LPA ) 的一个坡度。最后，我们发现了人口自发地转变了成对方的那个 OEC 代用品。一起，这些结果示威，第一次到我们的知识，不同 OEC 潜水艇人口显示不同迁移的性质试管内并且提供新证据当一个单个房间与韧性的功能的显型打字，支持 OEC 的观点。

英文摘要：

Olfactory ensheathing cells （OECs） are a unique type of glial cells that have axonal growth-promoting properties. OEC transplantation has emerged as a promising experimental therapy of axonal injuries and demyelinating diseases. However, some fundamental cellular properties of OECs remain unclear. In this study, we found that the distinct OEC subpopulations exhibited different migratory properties based on time-lapse imaging of single isolated cells, possibly due to their different cytoskeletal organizations. Moreover, OEC subpopulations displayed different attractive migratory responses to a gradient of lysophosphatidic acid （LPA） in single-cell migration assays. Finally, we found that OEC subpopulations transformed into each other spontaneously. Together, these results demonstrate, for the first time to our knowledge, that distinct OEC subpopulations display different migratory properties in vitro and provide new evidence to support the notion of OECs as a single cell type with malleable functional phenotypes.