中文摘要：

以取代度为0、0．51、1．01的葛仙米多糖硫酸酯为原料，探讨了各样品的抗凝血活性．结果表明：葛仙米多糖硫酸酯能显著延长人活化部分凝血活酶时间（APTT）和凝血酶时间（TT），且具有一定的剂量效应关系，但对凝血酶原时间（PT）的作用不明显．说明其主要是通过抑制内源性凝血过程及共同凝血途径发挥抗凝血作用，对外源凝血途径影响较弱．

英文摘要：

This paper investigated the anticoagulant activity of Nostoc Sphaeroides Kützing polysaccha-ride’ s sulfuric acid ester,whose substitution degrees were 0,0.51,1.01 respectively.The results showed：Nostoc Sphaeroides Kützing polysaccharide’ s sulfuric acid ester could obviously prolong APTT and TT, and depended on the concentration but did not play a significant role to PT.So the results mainly illustra-ted that it played the function of anticlotting through inhibiting endogenous blood coagulation process and conjunct blood coagulation way,but it showed weak effect on exogenous blood coagulation way.