中文摘要：

目的：比较完全腹腔镜和腹腔镜辅助根治性全胃切除术的临床疗效。方法：采用回顾性队列研究方法。收集2015年1月至2016年12月国内7家医疗中心收治的373例（青海大学附属医院82例、广东省中医院80例、厦门大学附属第一医院60例、杭州市第一人民医院51例、西安交通大学第一附属医院46例、吉林大学第二医院30例、第四军医大学西京医院24例）行腹腔镜根治性全胃切除术胃癌患者的临床病理资料。373例患者中，183例（青海大学附属医院63例、广东省中医院36例、厦门大学附属第一医院25例、杭州市第一人民医院20例、西安交通大学第一附属医院10例、吉林大学第二医院17例、第四军医大学西京医院12例）患者行完全腹腔镜根治性全胃切除术，设为完全腹腔镜组；190例（青海大学附属医院19例、广东省中医院44例、厦门大学附属第一医院35例、杭州市第一人民医院31例、西安交通大学第一附属医院36例、吉林大学第二医院13例、第四军医大学西京医院12例）患者行腹腔镜辅助根治性全胃切除术，设为腹腔镜辅助组。全组患者均采用常规5孔法行腹腔镜根治性全胃切除术，行D2淋巴结清扫术。消化道重建均采用Roux-en-Y吻合术，完全腹腔镜组患者消化道重建均在腹腔镜下完成，腹腔镜辅助组患者取腹上区正中辅助切口完成。观察指标：（1）手术及术后情况。（2）随访和生存情况。采用门诊和电话方式进行随访，了解患者术后总体生存、肿瘤复发、肿瘤转移情况。随访时间截至2017年3月。正态分布的计量资料以x±s表示，组间比较采用t检验。偏态分布的计量资料以M（范围）表示。计数资料比较采用x2检验或Fisher确切概率法。结果：（1）手术及术后情况：两组患者均顺利完成手术，无围术期死亡患者。183例完全腹腔镜组患者食管空肠吻合术方式：圆?

英文摘要：

Objective：To compare the clinical efficacies of totally laparoscopic and laparoscopyassisted radical total gastrectomies. Methods：The retrospective cohort study was conducted. The clinicopathological data of 373 patients with gastric cancer who underwent totally laparoscopic or laparoscopyassisted radical total gastrectomies from the 7 medical centers in China （82 patients in the Affiliated Hospital of Qinghai University, 80 in the Traditional Chinese Medicine Hospital of Guangdong Province, 60 in the First Affiliated Hospital of Xiamen University, 51 in the Hangzhou First People′s Hospital, 46 in the First Affiliated Hospital of Xi′an Jiaotong University, 30 in the Second Affiliated Hospital of Jilin University and 24 in the Xijing Hospital of the Fouth Military Medical University） between January 2015 and December 2016 were collected. Of 373 patients, the 183 and 190 patients were respectively divided into the totally laparoscopic group （undergoing totally laparoscopic radical total gastrectomy） and laparoscopyassisted group （undergoing laparoscopyassisted radical total gastrectomy）, including 63 and 19 in the Affiliated Hospital of Qinghai University, 36 and 44 in the Traditional Chinese Medicine Hospital of Guangdong Province, 25 and 35 in the First Affiliated Hospital of Xiamen University, 20 and 31 in the Hangzhou First People′s Hospital, 10 and 36 in the First Affiliated Hospital of Xi′an Jiaotong University, 17 and 13 in the Second Affiliated Hospital of Jilin University, 12 and 12 in the Xijing Hospital of the Fouth Military Medical University. Routine fiveport method was applied for laparoscopic radical total gastrectomy and D2 lymphadenectomy. RouxenY anastomosis was applied for digestive tract reconstruction, and digestive tract reconstruction was performed under laparoscopy in the totally laparoscopic group and via upper abdominal median incision in the laparoscopyassisted group. Observation indicators： （1） operation and postoperative situations; （2） followup and sur