登革热病毒(DENV ) 属于家庭 Flaviviridae 和它的类 Flavivirus 首先经由豹脚蚊 aegypti 和豹脚蚊 albopictus 蚊子被播送。DENV 的生命周期包括附件, endocytosis,蛋白质翻译, RNA 合成,集会,外出,和成熟。最近的研究显示了包括细胞的蛋白质和 microRNAs,许多主人因素断然或否定地调整 DENV 复制过程。这评论总结最近的调查结果(从 2014 ~ 2016 ) 在主人的鉴定,因素在 DENV 生命周期和登革热感染包含了。
Dengue virus (DENV) belongs to the genus Flavivirus of the family Flaviviridae and it is primarily transmitted via Aedes aegypti and Aedes albopictus mosquitoes. The life cycle of DENV includes attachment, endocytosis, protein translation, RNA synthesis, assembly, egress, and maturation. Recent researches have indicated that a variety of host factors, including cellular proteins and microRNAs, positively or negatively regulate the DENV replication process. This review summarizes the latest findings (from 2014 to 2016) in the identification of the host factors involved in the DENV life cycle and Dengue infection.