中文摘要：

目的：分离鉴定丹参内生真菌,考察其代谢产物粗提物的体外抗二磷酸腺苷（ADP）诱导的血小板凝集活性。方法：对丹参的叶、茎和根中的内生真菌进行分离,采用ADP诱导血小板凝集实验测试丹参内生真菌粗提物的抗血小板凝集活性,并用分子生物学方法对筛选出的活性内生真菌进行鉴定。结果：共分离得到80株内生真菌,发现5株内生真菌的粗提物具有良好的抗血小板凝集的作用。结论：丹参中分离的多种活性内生真菌具有潜在的抗血小板凝集活性,值得进一步研究和开发。

英文摘要：

Objective：To isolate and identify endophytic fungi fromSalvia miltiorrhiza Bge.and screen their anti-platelet aggregation activity.Methods：Endophytic fungi were isolated from the leaf,stem and root of Salvia miltiorrhiza Bge..The anti-platelet aggregation activity of endophytic fungi was detected with adenosine diphosphate（ADP）-induced platelet aggregation experiments.Then,active endophytic fungi were identified by molecular biological methods.Results：A total of 80endophytic fungi were isolated from Salvia miltiorrhiza Bge.,and the raw extracts from the 5strains showed significant anti-platelet aggregation activity.Conclusion：Several endophytic fungi of Salvia miltiorrhiza Bge.proved to have potential anti-platelet aggregation activity,and they were worth further research and development.