中文摘要：

炎症反应是机体对损伤和异物的正常应答,炎症的强度和持续时间影响生物材料在体内的相容性和稳定性。巨噬细胞是调控机体免疫和炎症反应的重要细胞,因此它对生物材料的响应性在认知材料-机体反应中有决定性作用。系统阐述巨噬细胞表型与机体创伤环境及对后期的修复和（或）再生、巨噬细胞表型与相关生物材料之间的相互作用,并对其未来发展方向进行评述。

英文摘要：

The body inflammatory reaction is a normal response to injury and the presence of foreign substances. The duration and intensity of inflammation has a direct impact on biocompatibility and stability of biomaterials in vivo. Macrophage is one of the major cell types in controlling body inflammatory and immune processes,hence,its response to biomaterials is critical for identifying the biomaterial-body reaction. In this review,the correlation between macrophage phenotype and injury as well as the tissue repair or regeneration,the interaction of macrophages with biomaterials,and the future development are introduced in detail.