Dynamin-related protein 1属于动力蛋白GTP酶超家族,是线粒体分裂体系的组成成分,在线粒体分裂中具有重要作用。在不同物种中,dynamin—related protein 1在与多种分子相互作用后,可以定位于线粒体并组装成高级结构,引起膜的收缩和分裂。Dynamin—relatedp rotein 1功能的消失会增强线粒体的融合和线粒体之间的连通性。Dynamin-related protein 1在细胞凋亡等多种细胞功能中也具有重要作用。
Dynamin-related protein 1 belongs to the dynamin GTPase superfamily. As the composition of mitochondrial fission system, Dynamin-related protein 1 plays an important role in mitochondrial fission. After interacting with a variety of molecules, Dynamin-related protein 1 can be located in mitochondria and assembled into higher structure, causing the contraction and fission of membranes in different species. The function loss of Dynamin-related protein 1 enhances mitochondrial fusion and connectivity. Dynamin-related protein 1 is also related to many kinds of cell functions such as apoptosis.