目的:主要基于磁感应的相关原理,设计一个采用对称抵消方式的线圈传感器,利用基于该线圈传感器的测量系统,对5名健康受试者的脑血流搏动进行测量。方法:总结国内外相关的磁感应测量方法,从提高灵敏度、减少干扰等方面设计新型线圈传感器;改进测量系统,提高抗干扰能力与软件鉴相能力;经脑测量人体脑血流搏动信号并对结果进行处理分析。结果:制作了一个由一个激励线圈、两个接收线圈组成的对称抵消方式的线圈传感器,完成了对称抵消测量系统的建立以及调试。挑选5名健康受试者进行实验,经脑测量的脑血流搏动信号规律清晰,干扰较小,其相位差变化量为0.1°~0.2°,根据受试者个体差异,测量的脑血流搏动的幅度和频率是不一样的。结论:该系统能够进行脑血流搏动测量,结果稳定,为脑血流相关检测提供了一个新方向。磁感应技术作为一种新的脑血流搏动信号检测手段,具有操作方便,非接触等特点,并且能够进行连续监测,在未来医疗监护、疾病诊断等方面具有很大的发展前景。
Objective The purpose of this paper is to design a coil sensor based on symmetrical offset way under the theory ofmagnetic induction and to measure cerebral blood flow pulsation of five healthy objects by measuring system based on the coilsensor. Methods The relevant magnetic induction measurement methods at home and abroad were summarized and the new coilsensor in consideration of improving the sensitivity and reducing interference and so on was designed. And the measurementsystem to enhance anti-jamming capability and software phase capacity was improved. Then we measured objects' cerebralblood flow pulsating signals and analyzed the results. Results We produced a coil sensor based on symmetry offset way by usingan excitation coil and two receive coils, and completed the establishment and debugging of the symmetry offset measurementsystem. Five healthy objects were selected for the experiment and their cerebral blood flow pulsating signals measured by thissystem were regular and clear and of less interference. The amount of change of phase was 0.1 % -- 0.2 % , and the amplitudeand fi'equency of cerebral blood flow pulse was different because of individual differences. Conclusion The system is capable ofmeasuring cerebral blood flow pulsation with the stable results. This provides a new direction for test of cerebral blood flow. Asa new means of cerebral blood flow pulsation signal detection, magnetic induction technology is easy to operate, non-contactand can be used in continuous monitoring. Magnetic induction technique is promising in health care and disease diagnosis.