中文摘要：

目的系统评价青少年（≥13岁）及成年人膈神经切取移位后对肺功能的长期影响。方法计算机检索1970年1月至2015年1月发表的有关膈神经移位术的国内、外相关文献，数据库包括PubMed、Cochrane、Embase、CBM、CNKI、维普、万方等，英文关键词为“phrenic nerve trans，respiratory function”，中文以“膈神经、肺功能、神经移位”为关键词检索。按照纳入标准，排除重复文献、动物实验后筛选适合文献，采用ReviewManager5．3软件进行Meta分析。结果共检索到208篇文献，最终符合要求的有10篇，其中中文5篇，英文5篇，涉及401例患者。Meta分析结果显示肺活量（Vc）、第一秒用力呼气量（FEV1）、残气量（RV）和功能残气量（FRC）的平均水平术前与术后半年及1年相比差异均无统计学意义；但术后半年VC和FEV1下降程度均比术后1年更明显。圣·乔治呼吸问卷（SGRQ）得分进行评定呼吸相关生活质量，总平均分、症状部分、活动部分及影响部分得分均显著高于参考值。结论膈神经移位术后半年肺功能就可以恢复至术前水平；膈神经移位后对呼吸相关的生活质量有损伤，但总体损伤较轻。

英文摘要：

Objective To evaluate the long-term influence on pulmonary function of the teenager（ i〉 13ys） and adult patients after phrenic nerve transfer and providing guideline for further clinical practice and research. Methods Detailed electronic and hand searches with no restrictions were performed for published paper about phrenic nerve transposition from January, 1970 to January, 2015. The PubMed, Cochrane Library, Embase database, CBM, CNKI database, VIP, Wanfang data were used for published paper searching. For foreign language paper, the key words were ＂phrenic nerve trans ＊ ＂, ＂respiratory function＂, and for Chinese literature searching, the key words were ＂phrenic nerve, pulmonary function, nerve transfer＂. The other sources as supplying, such as related references tracing, were also retrieved. The literature was screened according to inclusive criteria, and repeated docu- ments with animal experimental study were excluded. The data were extracted and the quality of included studies was assessed. Meta-analysis was conducted using Review Manager 5.3 software. Results A Total of 208 litera- tures were retrieved, and ultimately 10 articles met the requirements, including 5 Chinese and 5 English articles with 401 patients. In comparison to preoperative, the pulmonary function of VC, FEV1, RV and FRC after phrenic nerve transfer had no significant difference half a year postoperatively, and also, 1 year postoperatively. However, compared with 1 year after operation, the VC, FEV1 decline ratio of half a year postoperatively decreased significant. Assessment of quality of life related breathing with the St George＇s respiratory questionnaire score （SGRQ）, compared to the reference values of pulmonary function, except the scores of activities were no significant difference, the total average score, symptoms component scores and the impact components scores were significantly high-er. Conclusion The pulmonary function can be recovered to the preoperative level after phrenic nerve transfer half a ye