中文摘要：

目的：探讨慢性手部湿疹（chronic hand eczema,CHE）患者的心理社会因素.方法：收集CHE患者240例,正常对照（normal control,NC）221例,采用一般情况问卷、艾森克人格问卷（Eysenck Personality Questionnaire,EP囝、抑郁自评量表（Self-Rating Depression Scale,SDS）、焦虑自评量表（Self-Rating Anxiety,SAS）及湿疹患者生活质量量表（Eczema Quality of Life Scale,EQOLS）测评受试者人格特征、情绪状态、生活质量等心理社会因素及与疾病严重程度的相关性.结果：EPQ量表得分比较,CHE组内外向（E）维度得分显著低于NC组（P＜0.01）,神经质（N）维度得分显著高于NC组（P＜0.01）;精神质（P）维度和掩饰（L）维度得分两组间差异无统计学意义（P＞0.05）.CHE组的SDS量表和SAS量表得分均显著高于NC组（P＜0.01）.EQOLS量表得分比较,CHE组的疾病、心理、生理、社会各维度、量表总分及总体生活质量评分均显著高于NC组（P＜0.01）.CHE患者的皮损程度和与瘙痒水平与SDS,SAS,EQOLS量表的疾病、生理、心理、社会各维度、总体生活质量、总分均有显著相关性（P＜0.05）.结论：CHE患者个性更偏内向,情绪不稳定;抑郁、焦虑水平较高,生活质量水平下降,且均与病情严重程度相关.

英文摘要：

Objective： To study the psychosocial factors in patient with chronic hand eczema （CHE）. Methods： Personality traits, emotional state, and quality of life of 240 patients with CHE and 221 normal control （NC） subjects were assessed by General Questionnaire, Eysenck Personality Questionnaire （EPQ）, Self-Rating Depression Scale （SDS）, Self-Rating Anxiety （SAS）, and Eczema Quality of Life Scale （EQOLS）. Results. In comparison, EPQscores, scores of extraversion （E） factor in patients with CHE were significantly lower than those in NC subjects （P〈0.01）, but scores of neuroticism （N） factor in patients with CHE were significantly higher than those in NC subjects （P〈0.01）, while there was nosignificant difference in scores ofpsychoticism （P） and lie （L） factors between two groups （P〉0.05）. Patients with CHE had significantly higher scores in SDS and SAS compared with the NC subjects （P〈0.01）. Patients with CHE had significantly higher scores in scale of morbid, physical, social, psychological, general quality of life, and total scores of EQ_OLS compared with the NC subjects （P〈0.01）. The level of skin lesions and the degree of itch were significantly correlated with scores in scale SDS, SAS, morbid, physical, social, psychological, general quality of life, and total scores of EQ_OLS compared with the NC subjects （P〈0.05）. Conclusion： Personality of patients with CHE is prone to emotional instability of introverts. Patients with CHE have a higher level of depression and anxiety, and exert a negative effect on their quality of life, which is related to severity of disease.