中风的病因可概括为动脉的损害、血液流变学异常、血液动力学异常、血液成分异常及一些继发因素等。肿瘤患者的凝血活性增加、血管壁损伤和血管阻塞、血小板异常、纤溶系统异常和抗凝活性减弱等病理变化使患者机体处于易发血栓状态,而致中风。肿瘤早期多隐匿,症状不明显,可以血栓性疾病为首发疾病,临床中尚有部分中风病因不明确。明确隐匿性肿瘤形成静脉血栓的机制,结合中风的病因,可指导临床对无明显诱因中风的病因进行深入的研究,对无明显诱因的中风患者可考虑是否由隐匿性肿瘤所致。
The causes of stroke can be roughly summed up as the artery damage, abnormal blood rheology and blood dynamics, abnormal blood components and some secondary factors, etc. The pathological changes such as the increased blood coagulation activity, hemal wall injury, vascular obstruction, abnormal platelets, abnormal fibrinolytic system and weakness of anticoagulant activity may cause the body in a state of prone to blood clots and stroke. The incipient tumors are often hidden and its symptoms are not clear. They may induce thrombotic diseases and stroke. The etiology of stroke is not clear in clinic. The analysis of mechanism of venous thrombosis of occult tumor combined with the cause of stroke may guide the clinical research on stroke of no apparent cause. For patients with stroke of no apparent cause, we may consider it may be caused by occult tumor.