目的:探讨中医药防治抑郁症临床文献的用药规律。方法:对1979年1月至2011年12月在中国期刊全文数据、维普信息资源系统上发表的关于中医药或中西医结合防治抑郁症临床文献中有明确的药物组成及剂量的方剂进行药物统计分析。结果:中医治疗抑郁症的常用药物以补虚药最为常见,使用864次占总用药频次的23.9%,其他依次是活血化瘀药、理气药、安神药等;药物四性以温性药物使用频次最高1 416次,占39.2%;药物五味以苦、辛、甘最为常见,分别出现1 861次、1 752次、1 654次;药物归经以肝经最为多见,出现1 986次,占55.0%,其他出现10%以上的依次是心经、脾经、胃经、肺经、肾经等。结论:中医药防治抑郁症多使用具有补益正气、活血化瘀、疏肝理气、养心安神的药物,同时配合清热、利水渗湿、化痰、开窍、消食等药物,起到标本兼治的治疗作用。
Objective:To study the medication regularity research of TCM prevention and treatment of depression.Methods:The prescriptions with clear drugs composition and dosage in clinical literature published in "China journal full-text data" and "VIP information resource system" about Chinese medicine or combination of traditional Chinese and western medicine in prevention and treatment of depression were counted and analyzed.Results:Commonly used drugs of Chinese medicine treatment of depression was tonifying deficiency medicine,and use for 864 times,accounted for 23.9% of the total drug use frequency.The other was promoting blood circulation to remove blood stasis,and qi-regulating drugs,sedative medicine,etc.;Liver meridian was the common channel tropism,1986 times,accounted for 55.0%,and other appearance more than 10% of channel tropism were heart meridian,spleen meridian,stomach meridian,lung meridian,kidney meridian,etc.Conclusion:The mostly use drugs of traditional Chinese medicine prevention and treatment depression were benefiting the healthy qi,promoting blood circulation to remove blood stasis,tranquilizing by nourishing the heart,and coupled with clearing heat,promoting urination,reducing phlegm,inducing resuscitation and digestant drug,which can achieve the treatment roles of both symptoms and root causes.