中文摘要：

目的：研究茜草科粗叶木属植物长尾粗叶木Lasianthus acuminatissimus根中的化学成分。方法：利用正相、反相（RP-18）硅胶柱色谱、大孔树脂柱色谱和制备高效液相色谱分离，通过现代波谱技术（^13C-NMR，^1H-NMR，DEFF，EI-MS）鉴定结构。结果：分离鉴定了6个化合物，分别为：异东莨菪素（isoseopletin Ⅰ），异东莨菪索6-O-β-D-葡萄糖苷（isoscopletin-6-O-β-D-glucopyranosideⅡ），mudanoside-A的β构型体（Ⅲ），车叶草苷（asperulosideⅣ），（-）-pinoresinol4-O-D-glucopyranoside（Ⅴ），胡萝卜苷（Ⅵ）。结论：这些化合物均是首次从粗叶木属植物中得到。

英文摘要：

Objective： To investigate the chemical constituents from the root of Lasianthus acuminatissirmus of Rubiaceae. Method：Normal, reverse phase silica gel, macroporous resin column and HPLC chromatography were used for isolation. Spectroscopic methods （^13C-NMR,^1H-NMR, DEFt, EI-MS） were used for identification. Result： Six compounds were isolated and elucidated as isoscopletin （ Ⅰ ）, isoscopletin-6- O-β-D-glucopyranoside （ Ⅱ ）, β configuration of Mudanoside-A （Ⅲ ）, asperuloside （ Ⅳ ）, （ - ）-pinoresinol 4- O-β-D-glucopyra- noside （ Ⅴ）, daucosterol （ Ⅵ ）. Conclusion： These compounds were obtained from this plant for the first time.