中文摘要：

转录组学是生命科学领域的一门交叉型、发展快速的前沿性学科。随着高通量测序技术的迅猛发展,在收集、整合及数据挖掘的基础上全面系统的研究转录组成为可能。目前,利用转录组学的理论及技术研究疾病的转录组信息,系统全面阐明其基因表达调控规律,构建其基因调控网络,已经成为医学研究领域的热点。通过在医学研究生中开展转录组学这门课程,使研究生掌握其中的科研思维和方法,帮助研究生更清晰地认识疾病发生发展的分子机制,并通过学习这门课程提高研究生的科研能力和水平。

英文摘要：

Transcriptomics is a newly emerging research field with interdisciplinary characteristics and rapid advances. With the rapid development of high-throughput sequencing technology, it makes study transcriptomics in the overall system possible that depends on the collection, integration and data mining. At present, elucidation of gene expression and construction of the gene regulatory network have already become the focus of medical research through the theory and technology of transcriptome information. To help the postgraduates clearly understand the molecular mechanism of disease development, it is necessary to offer transcriptomics courses in medical postgraduates. Transcriptomics will be a powerful method to investigate the pathophysiologic mechanism and find the novel treatment of disease, which contributes to improving scientific research ability of the medical postgraduates.