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ANGPTL4基因的表达调控及功能研究进展
  • ISSN号：1001-9111
  • 期刊名称：《中国牛业科学》
  • 时间：0
  • 分类：S823.2[农业科学—畜牧学;农业科学—畜牧兽医]
  • 作者机构：[1]西北农林科技大学动物科技学院,陕西杨凌712100
  • 相关基金：本研究受国家自然科学基金（30771544）和“863”计划项目（2006AA10Z197,2006AA10Z1 A1）、“十一·五”科技支撑计划项目（2006BAD01A10）及西北农林科技大学博士基金（01140516）资助.
作者： 马云[1], 李荣荣[1], 侯飞[1], 陈宏[1]
关键词： 类血管生长因子4(ANGPTL4)基因, 表达调控, 血管生成, 脂类代谢, 葡萄糖代谢, Angiopoietinlike 4 （ ANGPTL 4） gene , Regulation of gene expression, Angiogenesis , Lipid metabolism , Glucose metabolism
中文摘要：

类血管生长因子4（ANGPTL4）是最新发现的与血管生成、脂类代谢、葡萄糖代谢、肿瘤及代谢性疾病相关的分泌性蛋白质因子。本文从ANGPTL4基因的基本结构、基因表达调控、基因功能及其与肿瘤及代谢性疾病的关系等四个方面对其研究进展进行了综述,并对ANGPTL4蛋白应用于治疗肥胖症、高甘油三酯血症以及各种血管病的前景做了展望。

英文摘要：

ANGPTL 4, a member of the angiopoietin-related protein family, which was found recently and related with angiogenesis, lipid metabolism, glucose metabolism, cancer and metabolic diseases. Research progress of basic structure, regulation of gene expression, main function and relationship with cancer and metabolic diseases for ANGPTL 4 gene were summarized in this paper and prospect of treating blood disease, obesity, hyperlipidaemia for ANGPTL 4 protein were forecasted.

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期刊信息
  • 《中国牛业科学》
  • 主管单位:中华人民共和国教育部
  • 主办单位:西北农林科技大学 中国畜牧兽医学会养牛学分会 中国良种黄牛育种委员会
  • 主编：陈宏
  • 地址：陕西杨凌西北农林科技大学西农校区动物科技学院内
  • 邮编：712100
  • 邮箱：huangn2002813@aliyun.com
  • 电话：029-87091423
  • 国际标准刊号：ISSN：1001-9111
  • 国内统一刊号：ISSN：61-1449/S
  • 邮发代号:52-113
  • 获奖情况:
  • 全国中文畜牧学核心期刊,全国畜牧兽医优秀期刊,陕西省优秀科技期刊
  • 国内外数据库收录:
  • 英国农业与生物科学研究中心文摘
  • 被引量:2954