目的:对毛茛科唐松草属植物华东唐松草的化学成分进行研究。方法:利用多种色谱技术进行分离纯化,通过理化性质和波谱数据鉴定化合物的结构。结果:从华东唐松草中分离鉴定了10个化合物,分别为:岩白菜素(1)、1-(4-hydroxy-3-methoxy)-phenyl-2-[4-(1,2,3-trihydroxypropyl)-2-methoxy]-phenoxym-1,3-propandiol(2)、4-(2-羟乙基)-2-甲氧基苯基-β-D-吡喃葡萄糖苷(3)、meliasendanin D(4)、2-(4-羟基-3-甲氧基苯基)-乙基-O-β-D-吡喃葡萄糖苷(5)、常春藤苷C(6)、2-(3-羟基-4-甲氧基苯基)-乙基-O-β-D-吡喃葡萄糖苷(7)、β-谷甾醇(8)、3-O-β-Dglucopyranosyl(1→6)-β-D-glucopyranosyl(22S,24Z)-cycloart-24-en-3β,22,30-tetraol-26-O-β-D-glucopyranoside(9)、3-O-β-D-quinovopyranosyl(1→6)-β-D-glucopyranosyl(1→4)-β-D-fucopyranosyl(22S,24Z)-cycloart-24-en-3β,22,26-triaol-26-O-β-D-glucopyranoside(10)。结论:其中,化合物1~6为首次从该植物中分离得到。
Objective: To investigate the chemical constituents of Thalictrum fortunei. Methods: Compounds were separated and purified by chromatographic methods and the structures were identified by their physicochemical properties and spectroscopic data. Results: Ten compounds were isolated and identified as bergenin( 1),1-( 4-hydroxy-3-methoxy)-phenyl-2-[4-( 1,2,3-trihydroxypropyl)-2-methoxy]-phenoxym-1,3-propandiol( 2) 、4-( 2-hydroxyethyl)-2-methoxyphenyl-O-β-D-glucopyranoside( 3),meliasendanin D( 4),2-( 4-hydroxy-3-methoxyphenyl)-ethyl-O-β-D-glucopyranoside( 5),kizutasaponin C( 6),2-( 3-hydroxy-4-methoxyphenyl)-ethyl-O-β-Dglucopyranoside( 7),β-sitosterol( 8),3-O-β-D-glucopyranosyl( 1→6)-β-D-glucopyranosyl( 22 S,24Z)-cycloart-24-en-3β,22,30-tetraol-26-O-β-D-glucopyranoside( 9) and 3-O-β-D-quinovopyranosyl( 1→6)-β-D-glucopyranosyl( 1→4)-β-D-fucopyranosyl( 22 S,24Z)-cycloart-24-en-3β,22,26-triaol-26-O-β-D-glucopyranoside( 10). Conclusion: Compounds 1 ~ 6 are isolated form this plant for the first time.