中文摘要：

目的：通过宁养肿瘤患者资料的统计分析,探讨影响肿瘤患者生存预后的相关因素,为肿瘤的临床决策提供参考。方法：收集我院宁养院2010年1月至2012年12月收治的1 144例晚期肿瘤患者的病历资料,并进行随访调查及回顾性研究,采用Kaplan-Meier法计算生存期、生存率和绘制生存曲线,log-rank法比较生存率差异,多因素分析采用Cox比例风险模型。结果：因所患肿瘤死亡病例的平均生存期为20.2个月,中位生存期为9.5个月,1年累积生存率为（43.0±1.5）%,5年累积生存率为（6.5±0.8）%。多因素分析显示,性别、文化程度、对病情了解情况、是否接受过相关治疗（手术治疗、化疗或放疗）、出现疼痛的时间、疼痛治疗史、NRS评分和KPS评分是宁养肿瘤患者生存预后的独立影响因素。结论：了解宁养肿瘤患者的病情并进行积极有效的治疗以及早期进行疼痛控制是延长患者生存期的主要手段。

英文摘要：

Objective： To explore the influence of various factors on survival prognosis of cancer patient in hospice care and to provide evidence for clinical decision and treatment of cancer. Methods： 1 144 cancer pa-tients who received hospice service from Janurary 2010 to December 2012 participated in follow-up investi-gation and retrospective analysis. Survival time and survival rate were analyzed, and survival curve was drawn by Kaplan-Meier method. Significant difference was evaluated by the log-rank test. Multivariate a-nalysis of variables was performed using the Cox proportional hazard regression. Results： The average survival time of all the patients who died of cancer was 20.2 months and the median survival time was 9.5 months. The 1-year cumulative survival rate was （43.0!l. 5）X and the 5-year cumulative survival rate was （6.5~0.8）%. Multivariate analysis showed that gender, educational level, awareness of illness, re- ceiving operations or not, chemotherapy, radiotherapy, time of pain appearing, past history of pain treatment, Numeric Rating Scale （NRS） and Karnofsky Performance Status （KPS） score are the independent factors of survival time. Conclusion： Awareness of illness, effective treatment and pain control are significant to prolong survival time of cancer patients.