中文摘要：

目的：为了从传统中药山柰中寻找新的活性化学成分。方法：应用D101大孔树脂，MCI，Sephadex LH-20和制备液相等色谱方法对山柰根茎的乙醇提取物中水溶性部分进行分离纯化。结果：两个新的C-1磺酸化双苯庚烷差向异构体从山柰根茎中分离得到，分别命名为山柰磺酸A（1）和山柰磺酸B（2），并通过波谱学方法鉴定化合物的结构。两个化合物的绝对构型是通过比较电子激发圆二色谱（ECD）以及化学计算结合M02（OAc）4诱导圆二色谱（IcD）的方法确定。结论：化合物1和2为新化合物，并且首次对这两个化合物的绝对构型进行了确定。

英文摘要：

AIM： To discover new bioactive constituents from Kaempferia galanga L. （Zingiberaceae）. METHODS： The extract of K. galanga was divided into the chloroform and water-soluble portions. The latter fraction was successively subjected to column chromatography over a D101 macroporous adsorption resin, MCI, Sephadex LH-20, and preparative HPLC to obtain two compounds. RESULTS： Two novel sulfonated diarylheptanoid epimers, namely kaempsulfonic acids A （1） and B （2）, were isolated from the rhizomes ofK. galanga. Their structures were established by analysis of spectroscopic data. The absolute configurations of 1 and 2 were determined by the comparison of experimental electronic circular dichroism （ECD） spectroscopy and the computational calculation method, combined with Mo2（OAc）4 induced circular dichroism （ICD）. CONCLUSION： The isolates 1 and 2 are new compounds and their absolute configurations were determined for the first time.