中文摘要：

采用油水两相溶液体系，借助于双亲聚合物包覆实现了CdSe/ZnSe核壳结构量子点自油相到水相的相转移。油水两相中的聚合物包覆与已经报道的均相溶液中聚合物包覆量子点的方法不同，包覆过程在油水两相界面处完成，有效地减少了聚合物缠绕引起的量子点团聚，实现了聚合物对量子点的无团聚单分散包覆。透射电镜和激光粒度分析仪对聚合物包覆量子点的表征结果表明获得的水溶性量子点具有良好的分散性，均一的水力尺寸。吸收和发射光谱表明聚合物包覆过程对量子点的发射峰位和峰型没有引起明显的改变，维持了较高的量子产率。通过荧光微区成像技术成功实现了对人IgG蛋白的特异性检测，证实这种方法获得的聚合物包覆量子点具有较好的与生物分子偶联的功能化基团，适合于生物学标记应用。

英文摘要：

In the present work, the CdSe/ZnSe core/shell quantum dots （QDs） were successfully transferred from organic phase to water phase v/a a two-phase solution system process by surface coating with amphiphilic polymer. Surface coating with am- phiphilie polymer is an effective method, which can form stable soluble QDs in water. However, the conventional polymer coat- ing method is performed in homogeneous phase, and it easily induces the aggregation of the QDs attributing to the long chain of enlace of the polymer. It is thus necessary and meaningful to develop surface coating technique for getting monodisperse coating QDs with amphiphilic polymer. In comparison with previously reported coating method, the authors＇ experiment process is per- formed in two-phase solution system, and can effectively reduces the possibility of aggregation of the QDs. The resulting hydro- philic CdSe/ZnSe core/shell QDs have long term stability in water, and high quantum yield. The polymer coating process was af- firmed by various characterizations. Fourier transform infrared spectra suggest that the octylamine modified polymer was suc- cessfully coated on the surface of the CdSe/ZnSe QDs. The transmission electron microscopy suggests that the size and shape of the QDs showed no obvious change before and after the coating process. Dynamic light scattering results indicate that the hydro- philic QDs exhibit narrow hydrodynamic size distribution with the mean hydrodynamic diameters of about 19.7 nrrL The lumines- cence properties of the QDs were investigated with photoluminescence spectra and ultraviolet-visible absorption spectra. This polymer coating process has less effect on luminescence capability. The quantum yield decreased from 43~ to 30~. Further, in order to confirm that the polymer capped QDs is bioeompatible, the QDs were used for specific detection of the human IgG with fluorescence mapping. The specific molecular recognition capacity of goat anti-human IgG-modified QDs confirms that the poly- mer coated QDs have compatib