中文摘要：

辐射诱导的认知障碍是多种类型细胞相互作用的结果,包括星形胶质细胞、内皮细胞、神经细胞、小胶质细胞和少突胶质细胞等。目前研究表明辐射会引起海马神经发生的减少,突触可塑性等神经功能的改变以及神经细胞炎性因子的升高。

英文摘要：

Radiation-induced cognitive impairment is hypothesized to occur because of dynamic interactions between multiple cell types,including astrocytes,endothelial cells,microglia,neurons,and oligodendrocytes. Current researche indicates that radiation-induced changes include the decrease in hippocampus neurogenesis,alterations of neuronal functions,particularly synaptic plasticity,as well as the elevation of neuroinflammatory cytokines.