中文摘要：

本文报道了益母草碱合成新方法。用化合物4和5作为关键中间体，在合成的过程中，由于这两种化合物在有机溶剂中具有较好的溶解性，使得关键缩合反应可以在较温和的反应条件下进行，最终以较好的产率得到目标化合物益母草碱。与已报道的益母草碱合成方法相比，合成产率由30％升至54％，反应时间也大大缩短。

英文摘要：

A new synthetic method of leonurine was developed. Leonurine 1 was synthesized from the key intermediates 4 and 5, two compounds with high solubility in dichloromethane which allowed the synthetic procedure to be performed under mild conditions and afforded 1 with a good yield. Comparing the previous methods, the yield was increased from 30% to 54%, time consumed was significantly reduced as well.