欢迎您！东篱公司
退出
-
申报数据库
-
立项数据库
-
成果数据库
-
项目获奖数据库
中文摘要：
采用微流控芯片非接触电导检测法测定片剂中的盐酸倍他司汀。采用1 mmol·L-1HAc和2 mmol·L-1NaAc（pH 4.5）为缓冲溶液,0.1 mmol·L-1SDS为添加剂,以2.40 kV分离电压,10 s进样时间,盐酸倍他司汀2 m in内可实现快速分离和检测。盐酸倍他司汀的线性范围为10~140μg.mL-1（r0.999 9）,检出限为1.0μg.mL-1（S/N 3）,RSD为1.2%,加标回收率为98.3%~101.7%。方法简便快速、重现性好,适用于药品生产质量控制。
英文摘要：
The betahistine dihydrochloride in its tablets was determined by the microfluidic chip with contactless conductivity detection with 1 mmol·L-1 HAc and 2 mmol·L-1 NaAc（pH 4.5） as buffer solution,0.1 mmol·L-1 SDS as additive.The betahistine dihydrochloride was separated and detected in 2 min at 2.40 kV separation voltage and 10s injection time.The linear dependence of the concentration of the betahistine dihydrochloride ranged from 10 to 140 μg·mL-1（r=0.9999）,with the detection limit of 1.0 μg·mL-1（S/N=3）,the RSD of 1.2% and the recoveries from 98.3% to 101.7%.The method was simple,rapid and well reproducible,and it could be used in the quality control of the product.
同期刊论文项目
同项目期刊论文
Electromagnetic induction detector for capillary electrophoresis and its application in pharmaceutic
Rapid determination of partition coefficients of pharmaceuticals by microchip capillary electrophore
A two-electrode system-based electrochemiluminescence detection for microfluidic capillary electroph
Analysis of arecoline in Semen Arecae decoction pieces by microchip capillary electrophoresis with c
Cobalt hexacyanoferrate modified multi-walled carbon nanotubes/graphite composite electrode as elect
Electro- chemiluminescence detection system for microchip capillary electrophoresis and its applicat
Development of a microchip-pulsed electrochemical method for rapid determination of L-DOPA and tyros
A beveled working electrode coupled to a sandglass shape detection cell: A strategy to improve the s
Direct electron transfer of glucose oxidase and biosensing for glucose based on PDDA-capped gold nan
An integrated microfluidic array system for evaluating toxicity and teratogenicity of drugs on embry
Rapid determination of creatinine in human urine by microchip electrophoresis with LED induced fluor
期刊信息
位置：