在小囊 rotundus 和联系勇气的淋巴的纸巾的 bursin 的分发被免疫组织化学的染色的方法与 anti-bursin monoclonal 在兔子调查抗体(McAb ) 2F9-4。结果显示包含 bursin 房间的外观在兔子与 morphodifferentiation 和生长过程与一致。Bursin 使在屋顶上皮和 mucosal 上皮,而且在小囊 rotundus 的小囊的幼芽的中心,屋顶, T 房间区域,离脚玻璃杯或瓷杯房间,内部上皮的淋巴细胞和帽子地区不仅分布式的房间免疫。这成立建议在小囊 rotundus 的包含 bursin 房间可能在肠的 mucosal 免疫起一个重要作用。
The distribution of bursin in sacculus rotundus and gut-associated lymphoid tissues was investigated in rabbit by immuno-histochemical staining method with anti-bursin monoclonal antibody (McAb)2F9-4. The results indicated that the appearance of the bursin-containing cells coincided with the morphodifferentiation and growth process in rabbit. Bursin immunized cells not only distributed in dome epithelium and mucosal epithelium, but also in follicular germinal center, dome, T-cell area, goblet cell, inter-epithelial lymphocyte and cap-zone of sacculus rotundus. This founding suggested that bursincontaining cells in sacculus rotundus might play an important role in intestinal mucosal immunity.