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吸烟对PCI术前男性冠状动脉心脏病“破坏性”血脂的影响
  • ISSN号:1673-4130
  • 期刊名称:国际检验医学杂志
  • 时间:2014
  • 页码:3162-3164
  • 期号:23
  • 便笺:50-1176/R
  • 分类:R541.4[医药卫生—心血管疾病;医药卫生—临床医学;医药卫生—内科学]
  • 作者地址:宁夏医科大学检验学院;宁夏医科大学总医院心脏中心;
  • 作者机构:[1]宁夏医科大学检验学院,宁夏银川750004, [2]宁夏医科大学总医院心脏中心,宁夏银川750004
  • 相关基金:宁夏卫生厅医疗卫生科研计划资助项目(2012047)。
中文摘要:

目的:分析吸烟对 PCI 术前男性冠状动脉心脏病(CHD)患者血脂的影响。方法随机抽取124例实施经皮冠状动脉治疗术(PCI)的男性 CHD 患者病例资料,分为吸烟组(88例)和非吸烟组(36例)。对年龄、既往病史、三酰甘油(TG)、总胆固醇(CHOL)、高密度脂蛋白(HDL)和低密度脂蛋白(LDL)等血脂进行回顾性调查研究。结果吸烟组的 LDL 为(3.1±1.34) mmol/L 高于非吸烟组[(2.5±0.95)mmol/L],比较差异有统计学意义(P <0.05);TG[(2.5±1.49)mmol/L]、HDL[(0.99±0.29)mmol/L]、LDL[(3.6±1.13)mmol/L]参数水平 CHOL(≥4.5 mmol/L 组较 CHOL<4.5 mmol/L 组 TG[(1.8±1.23) mmol/L]、HDL[(0.88±0.20)mmol/L]、LDL[(2.20±0.69)mmol/L]组高,差异有统计学意义(P <0.05);经过 Spearman 分析,发现血管病变数和 CHOL,LDL 水平呈正相关,同时吸烟程度和 LDLA 呈负相关。结论吸烟及 CHOL、LDL 水平与男性 CHD有密切关系,且吸烟可影响血脂代谢,可增加其患 CHD 的危险性。

英文摘要:

Objective To analyze the effect of smoking on blood lipid before percutaneous coronary intervention(PCI)in male coronary heart disease(CHD).Methods The clinical data in 124 cases of CHD with PCI were randomly extracted and divided into the smoking group (n = 88 )and the non-smoking group (n = 36 ).The age,past disease history,triglycerides (TG),cholesterol (CHOL),low density lipoprotein(LDL)and high density lipoprotein(HDL)were retrospectively investigated.Results The LDL level of the smoking group was(3.1±1.34)mmol/L,which was significantly higher than(2.5 ±0.95)mmol/L in the non-smoking group with statistical difference between them(P 〈0.05);the level of TG,HDL and LDL in the CHOL≥4.5 mmol/L group were (2.5±1.49)mmol/L,(0.99±0.29)mmol/L and(3.6 ±1.13)mmol/L respectively,which were hither than(1.8 ±1.23)mmol/L, (0.88±0.20)mmol/L and(2.2±0.69)mmol/L in the CHOL≤4.5 mmol/L group respectively,the differences among them had statistical significance(P 〈0.05 );the Sperman analysis found that there was a positive correlation between the level of vascular change with CHOL and LDL,at the same time the smoking level was negatively correlated with LDLA.Conclusion Smoking, CHOL and LDL have a close relationship with the male coronary heart disease.Moreover,smoking can affect the lipid metabolism and probably increase the risk of coronary heart disease.

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期刊信息
  • 《国际检验医学杂志》
  • 主管单位:重庆市卫生和计划生育委员会
  • 主办单位:重庆市卫生信息中心
  • 主编:府伟灵
  • 地址:重庆市渝中区宝环路420路
  • 邮编:401120
  • 邮箱:gwyxwd@163.com
  • 电话:023-63616134
  • 国际标准刊号:ISSN:1673-4130
  • 国内统一刊号:ISSN:50-1176/R
  • 邮发代号:78-26
  • 获奖情况:
  • 卫生部首届医药卫生优秀期刊奖三等奖,重庆市一级期刊
  • 国内外数据库收录:
  • 美国化学文摘(网络版),波兰哥白尼索引,美国剑桥科学文摘
  • 被引量:32189