中文摘要：

在室温下用气体扩散的方法,以胃蛋白酶为基质,在水和乙醇的混合溶剂体系中,仿生合成了球形的球霰石晶型碳酸钙.相较于在没有基质作用的纯水体系中得到的晶体,发现在蛋白质的指导下,碳酸钙的结晶习性发生了改变,由不规则块状变为球状结构,晶型也由方解石型转化为球霰石型,为控制合成特殊形貌的材料提供了新的途径.通过对产品进行扫描电子显微镜测试（SEM）,X射线粉末衍射（XRD）,热重差热分析（TG-DTA）,傅里叶转换红外光谱分析（FT-IR）,荧光分析（PL）和比表面积（BET）表征,从分子水平认识了基质和碳酸钙之间的相互作用,并尝试讨论其可能的形成机理.

英文摘要：

Calcium carbonate/pepsin（CaCO3/pepsin） hybrid crystals with sphere shape have been biomimetically synthesized in an ethanol/water solution with the pepsin as additive at ambient temperature.Calcium chloride,ethanol,double-distilled water and pepsin were used as the raw materials for the synthesis.In the controlled experiments,there was a change in the morphology of the particles.It could be attributed to divisive effect of the mixed solvents on growth morphology of CaCO3 crystals,namely,the different influences of the mixed solvent on the solubility of Ca2＋ and CO32-.The additional ethanol could change the solution viscosity,the dielectric constant of the solution,and then it would lead to the change of supersaturation which crystallization depends much on.The results display both the pepsin and ethanol in the initial solution could affect the morphology or crystalline polymorph of the CaCO3 particles.When the volume ratio of ethanol to double-distilled water was around 1∶1,CaCO3 crystals in the uniform morphology of sphere and the polymorph of vaterite were obtained.The crystals were characterized by X-ray powder diffraction（XRD）,scanning electron microscope（SEM）,Fourier transform infrared（FT-IR） spectroscopy,thermogravimetry-differential thermal analysis（TG-DTA）,photoluminescence（PL） spectroscopy and Brunauer-Emmett-Teller（BET）.The possible mechanism about the formation of the CaCO3/pepsin hybrid crystals was discussed.