中文摘要：

天然抗菌肽主要由无脊椎动物、脊椎动物和植物的组织或者细胞表达分泌而来,其种类繁多,结构复杂.各类抗菌肽由于其结构和组成的不同导致其作用机制也各不相同.但由于抗菌肽主要作用于靶细胞的质膜,因此关于抗菌肽作用机制的研究也主要集中在对靶细胞质膜结构影响的研究.文中综述了近年来抗菌肽抑菌机制研究中质膜相关研究方法,旨在为开展新型抗菌肽作用机制研究提供参考.

英文摘要：

Antimicrobial peptides are an abundant and diverse group of molecules that are produced by many tissues and cell types in a variety of invertebrate,vertebrate and plant species.Accordingly,difference of structure and composition led to different mechanism. This brought some difficulties to study and discuss their mechanism. In this paper membrane-associated study methods of antimicrobial mechanism were introduced,which would provide reference for the study on working mechanisms of antimicrobial peptides.