中文摘要：

真核细胞中的物质交流是通过膜泡运输完成的。膜泡运输主要包括运输囊泡的出芽、定向移动、拴留、锚定和膜融合过程。其中,拴留过程是运输囊泡和靶膜最初的接触。在此过程中,有许多因子参与调控,如拴留因子、小GTPase、SNARE蛋白等。GARP（golgi-associated retrograde protein）复合体是内涵体到高尔基体反面网状结构（TGN）逆行运输过程中的拴留因子。目前,关于GARP复合体的组成和功能已经有了一定的了解,本文将对GARP复合体的最新研究进展进行概述。

英文摘要：

In eukaryotic cells,the material communication is accomplished by vesicle transport. Vesicle transport includes the process of vesicle budding,directional transport,tethering,docking and fusion. Tethering process is the initial contact between transport vesicles and target membrane. In this process,there are many factors involved in regulation,such as tethering factors,small GTPases,SNAREs and so on. GARP（golgi-associated retrograde protein） complex is a tethering factor in endosome-to-TGN retrograde transport. Currently,there is a certain understanding about the structure and function of GARP. This review would summary the recent research progress of GARP complex.