中文摘要：

潜水艇的背景自体同源的移植进有微脉管的吻合的时间的窝的 mandible 的腺(SMG ) 成功地作为一个永久眼泪代用品在严重干眼病病人被使用了。然而，严重干眼病能被唾液的腺机能障碍伴随，做如此的自体移植不合适。因此， SMG 紧密相联的移植可能是一个答案。这研究的目的是估计潜水艇的技术可行性 mandible 的腺紧密相联的移植。12 头缩小的猪被使随机化用作施主或接受者的方法。一 SMG 在一个施主和一个接受者之间被移植。施主 SMG 是由它到接受者的脉管的小花梗的微脉管的吻合的 revascularized 语言的动脉和外部颈部的静脉。能分泌的管通过一条下的隧道被植入进嘴的门厅。没有抑制免疫力的代理人被管理。结果被移植 SMG 的分泌物，和组织病理学说的检查的视觉检查估计。技术上结果，所有外科的过程是成功的。一旦， Clearsecretion 从管流动了移植潜水艇的血供应 mandible 的腺被重建。腺的分泌物持续了 5 天。是期望，因为没有抑制免疫力的代理人被使用，尖锐拒绝反应发生在外科以后。从在 5 天以内停止的移植 SMG 的分泌物。SMG 紧密相联的移植的一个模型能在缩小的猪被建立的结论。潜水艇的技术 mandible 的腺紧密相联的移植是可行的。

英文摘要：

Background Autologous transplantation of the submandibular gland （SMG） into the temporal fossa with microvascular anastomosis has been successfully applied in severe xerophthalmia patients as a permanent tear substitute. However, severe xerophthalmia can be accompanied by salivary gland dysfunction, making such autotransplantation unsuitable. Therefore, SMG allotransplantation might be a solution. The aim of this study was to assess the technical feasibility of submandibular gland allotransplantation. Methods Twelve miniature swine were randomized to serve as donors or recipients. One SMG was transplanted between a donor and a recipient. The donor SMG was revascularized by microvascular anastomosis of its vascular pedicle to the recipient lingual artery and external jugular vein. The secretory duct was implanted into the vestibule of the mouth through a subcutaneous tunnel. No ilnmunosuppressive agent was administered. The results were assessed by visual inspection of the secretion, and histopathological examination of the transplanted SMG. Results Technically, all surgical procedures were successful. Clear secretion flowed out of the duct as soon as blood supply of the transplanted submandibular gland was reestablished. The secretion of the gland lasted for 5 days. As expected, an acute rejection reaction occurred after surgery because no immunosuppressive agents were used. Secretion from the transplanted SMG ceased within 5 days. Conclusions A model of SMG allotransplantation can be established in miniature swine. The technique of submandibular gland allotransplantation is feasible.