目的:探讨重症肠瘘病人早期肠内营养(EEN)结合消化液回输对康复的影响. 方法:我科收治的209例重症肠瘘病人,于人ICU 48 h内开始接受EN,次日开始回输漏出的消化液,在回输前后分别测定血清总蛋白(TP)、清蛋白(ALB)、前清蛋白(PA)、转铁蛋白(TF)、纤维连接蛋白(FN)、血红蛋白(Hb)等营养指标和部分电解质. 结果:消化液回输后7d,病人的血清TP、ALB、PA、TF、FN、Hb等均有所升高,与回输前比差异有显著性统计学意义(P <0.05,P<0.01).体重指数(BMI)也从回输前的17.58±1.09增加至回输后的18.23±1.11(P<0.01). 结论:EN结合消化液回输能明显改善重症肠瘘病人的营养状况,有利于早日康复.
Objective:To investigate the influence of early EN combined with digestive juice reinfusion on rehabilitation in severe intestinal fistula patients.Methods:209 severe intestinal fistula patients were recruited during July,2009 to December,2012.EN was performed in 48 hours after they were admitted to ICU,and digestive juice were infused back into the patient in the second day.Serum albumin,prealbumin,transferrin,hemoglobin and electrolytes etc.were monitored before and 7days after reinfusion,respectively.Results:Serum albumin was (33.98 ± 4.48) g/L and (35.31 ± 7.03) g/L,hemoglobin (126.61 ± 17.61) g/L and (130.03 ± 8.89) g/L,prealbumin (186.20 ±40.34) g/L and (257.02 ± 107.46)g/L,and fibronectin (164.33 ±22.44) mg/L and (225.14 ±40.13) mg/L.BMI increased from 17.58 ± 1.09 to 18.23 ± 1.11,P 〈 0.01.Conclusion:Early EN combined with digestive juice reinfusion can apparently improve the nutritional status of severe intestinal fistula patients.