中文摘要：

开展了动物内脏中14种酞酸酯类（PAEs）环境激素残留的气相色谱-电子轰击离子源质谱（GC-EI/MS）分析方法的研究,优化与选择了动物内脏样品的前处理条件。动物内脏样品经正己烷-二氯甲烷（体积比为1∶1）混合提取剂超声提取、Florisil硅土固相萃取柱净化与乙酸乙酯-正己烷（体积比为2∶3）混合洗脱剂洗脱和浓缩后,以邻苯二甲酸二苯基酯（DPhP）为内标物,采用GC-EI/MS的选择离子检测方式（SIM）进行定性和定量分析。当猪肝样品的加标浓度水平为100,200,400μg/kg时,加标回收率为60%～110%,相对标准偏差为0.8%～10.3%。除邻苯二甲酸二甲氧基乙酯（DMEP）与邻苯二甲酸二（2-乙氧基乙基）酯（DEEP）的方法检出限（MDL）分别为3.30μg/kg与2.25μg/kg外,其余12种PAEs的MDL均不大于1.74μg/kg;线性范围为50.0～800.0μg/kg,相关系数均大于0.9994。该分析方法已成功地应用于6种动物内脏中14种痕量PAEs残留的分析。

英文摘要：

An analytical multiresidue method was developed for the simultaneous determination of 14 phthalate esters （PAEs） in animal innards by gas chromatography-mass spectrometry with electron impact ionization （GC-EI/MS）. After the optimization of different parameters such as the extraction solvent, PAEs were extracted from animal innards with hexane-dichloromethane （1∶1, v/v） in an ultrasonic bath and cleaned up on a Florisil column, then were determined by GC-EI/MS in selected ion monitoring mode with diphenyl phthalate （DPhP） as internal standard. The recovery studies were performed at 100, 200 and 400 μg/kg levels for each PAE, and the recoveries ranged from 60%-110% with the relative standard deviations between 0.8% and 10.3% for different PAEs. The detection limit of the method was less than 1.74 μg/kg for most of PAEs except dimethoxyethyl phthalate （DMEP） and di（2-ethoxyethyl） phthalate （DEEP）. The method was linear over the range of 50.0-800.0 μg/kg with the correlation coefficients larger than 0.999 4. The method has been successfully applied to the determination of 14 PAEs in six animal innards.