中文摘要：

利用氯官能化己内酯（αClεCL）和未改性己内酯（CL）单体的开环聚合制备了氯官能化聚己内酯[P（CL-co-αClεCL）],然后将卤素转化为叠氮基团,利用叠氮和炔基间的点击化学反应制备了聚己内酯（PCL）接枝聚乙二醇（PEG）的两亲性接枝共聚物,并研究了接枝共聚物在水溶液中的胶束化自组装.发现PCL-g-PEG接枝共聚物在水溶液中可自组装为以PCL 为核层、PEG 为壳层的胶束.PCL-g-PEG 的临界胶束浓度（CMC）值为30-66 mg/L,流体力学半径（Dh）为104-136 nm.随着接枝链长度的增加,CMC 值和Dh 增大;当接枝链长度一定时,随着接枝密度的增大Dh 减小.

英文摘要：

The chloro-functionalized poly(ε-caprolactone) [P(CL-co-αClεCL)] was prepared by the ring-opening polymerization of chloro-functionalizedε-caprolactone (αClεCL) and unsubstitutedε-caprolactone (CL). The halide groups of P(CL-co-αClεCL) were then converted to azides. The amphipathic graft copolymers (PCL-g-PEG) bearing the PCL backbone and poly(ethylene glycol) (PEG) grafting chain were prepared by the azide-alkyne click chemistry and their micellar self-assembly in the aqueous solution was investigated. It was found that the PCL-g-PEG graft copolymers self-assembled into the micelles containing the PCL core and PEG shell in the aqueous solution. The critical micelle concentration(CMC) of graft copolymers were in the range of 30 mg/L to 66 mg/L and theirDh values were in the range of 104 nm to 136 nm. TheCMC andDh of graft copolymers increased with the grafting length. At the same grafting length,Dh increased as the grafting density was decreased.