海参味美可口,营养丰富,具有较高的药用价值,在我国一向被视为佐膳珍品,中医认为:"其性温补,足敌人参,故曰海参"。文章通过对近年来一些国内外文献进行整理,简要概括海参中的抗肿瘤活性成分的研究状况以及临床复方的应用情况。海参中含有多种抗肿瘤活性成分,主要有海参多糖和海参皂苷。这些抗肿瘤活性成分在肿瘤发生发展及转移的不同阶段,起着重要作用。海参中新的抗肿瘤活性成分的发现,对海参的抗肿瘤临床应用具有推动作用。
In order to sum up the antineoplasmic active components of Holothuria, we studied the literatures in recent years. The results showed that Holothuria contained a variety of anti-tumor active ingredient, such as Holotharian Glycosaminoglycan and Holothurin. These anti-tumor active components played important roles in different stages of tumor developmment, progression and metastasis. The discovery of new anti- tumor active ingredients may be helpful for the application of Holothuria in clinical tumor treatment.