中文摘要：

目的了解准噶尔盆地鼠疫自然疫源地动物鼠疫流行的空间和时间分布特征。方法对2005--2012年准噶尔盆地鼠疫自然疫源地大沙鼠血清鼠疫抗体检测数据，采用统计学方法并结合地理地貌特征，分析鼠疫抗体阳性率的空间分布及其时间变化。结果共获得准噶尔盆地13个行政区域大沙鼠血清鼠疫抗体检测数据4825份。大沙鼠动物鼠疫主要流行于准噶尔盆地中东部的古尔班通古特沙漠荒漠（阳性率为8．39％）和准噶尔盆地西部低山平原粘土荒漠（阳性率为1．56％）2个地区。准噶尔盆地西部地区鼠疫抗体阳性率由2005年的7．59％下降至2008年的0．61％，其后一直处于静息状态。东部古尔班通古特沙漠荒漠地区的东、中、西3个区段鼠疫抗体阳性率变化有所不同，西段于2006年和2010年间出现2次流行高峰，其间隔期为4年，2010年高峰期鼠疫抗体阳性率则达到45．65％，为3个地理区段最高值；中段于2006、2009和2011年出现3次高峰，间隔期为2．5年，鼠疫抗体平均阳性率为8．92％，流行强度低于东、西段；东段是大沙鼠鼠疫最活跃的地区，各年度均可检出鼠疫抗体阳性血清，其变化呈现2006、2009和2012年3个高峰期，间隔期为3年。大沙鼠鼠疫抗体检测阳性率秋季高于春季，说明大沙鼠鼠疫流行为春季至秋季的持续流行。结论准噶尔盆地大沙鼠鼠疫流行存在地理区域和时间上的双重波动，以及地理区域上的异质性，并可分为准噶尔盆地西部低山平原粘土荒漠和中东部古尔班通古特沙漠荒漠2个流行区域。

英文摘要：

Objective To explore the spatial and temporal distributions of animal plague in Junggar Basin natural plague focus. Methods Data regarding plague antibody （F1） in serum of Great Gerbil （Rhombomys opimus, R. opimus） which were collected from 2005 to 2012 in Junggar Basin and analyzed. The changing rates on the positivity of F1 that appeared spatially and temporally were also analyzed. Results A total of 4 825 R. opimus serum samples were collected in 13 administrative regions in Junggar Basin. Results showed that plague R. opimus existed in two areas-Gurbantonggut desert in the eastern-center and the clay desert of western Junggar Basin. However, in these two areas, the intensity of animal plague prevalence was different. In the former region where Yesinia pestis positive serum was detected from R. opiraus, the detected rate of R. opimus was 8.39%. However, in the latter areas, the average positive rate was 1.56%. The changing trends of R. opimus plague prevalence were also varied annually. In the western Junggar Basin, the trend showed a slowly downward profile. The serum positive rate of R. opimus for Yesinia pestis decreased, from 7.59% in 2005 to 0.61% in 2008, and appeared as a resting state that none of the positive sample could be found since then. However, in the eastern-center Junggar Basin area-also named as Gurbantonggut desert which had been divided into 3 segments （western, central and eastern, according to related geographical characteristics）, the changing trends of animal plague seemed quite complex. In the western segment, the animal plague had two epidemic peaks-in 2006 and 2010, with the interval of 4 years, with the higher peak of all the three geographic segments as 45.65% in 2010 and the positive serum ofR. opiraus for plague could be detected each year from 2006 to 2012. However, there were 3 epidemic peaks in the same period in the central and eastern segments. In the central segment, the peaks appeared in 2006,2009 and 2011, with the intervals as 2.5 years and the average posit