中文摘要：

代谢组学迅猛发展,自身特点及科研使命决定了其整合化的必然趋势。近年来,代谢组学经历了内部整合（包括：检测技术整合、多样本整合分析、数据处理方法整合）以及外部整合（代谢组学与其它组学的整合分析）。整合化发展增强了代谢组学在其应用领域的科学创新性与说服力。本文综述了代谢组学的整合化及其最新研究进展,并展望了其应用前景。

英文摘要：

Metabonomics studies have an inevitable tendency of integration determined by their own characteristics and research mission.In the past few years,integrated development of metabonomics underwent internal integration （including technology integration,integrated analysis of various samples and integration of data processing methods） and external integration （integrated metaonomics and other omics analysis）.The integration enhanced scientific foundation for metabonomics and lead scientific and technological innovation.In this paper,new progress on integrated development of metabonomics was reviewed,and the related application was prospected.