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GA3, a new gambogic acid derivative, exhibits potent antitumor activities in vitro via apoptosis-involved mechanisms
  • ISSN号：1671-4083
  • 期刊名称：《中国药理学报：英文版》
  • 时间：0
  • 分类：R378.25[医药卫生—病原生物学;医药卫生—基础医学] R979.1[医药卫生—药品;医药卫生—药学]
  • 作者机构：[1]Division of Antitumor Pharmacology ,State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China, [2]Department of MedicinaI Chemistry, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China
  • 相关基金：Acknowledgement This work was financially supported by the National Natural Science Foundation of China （No 30721005）. Hua XIE especially appreciated the support from a Shanghai Postdoctoral Grant （No 05R214157）.
作者： Hua XIE[1], Yu-xin QIN[1], Yun-long ZHOU[2], Lin-jiang TONG[1], Li-ping LIN[1], Mei-yu GENG[1], Wen-hu DUAN[2], Jian DING[1]
关键词： 细胞凋亡机制, 抗肿瘤活性, 新藤黄酸, 赤霉素, 衍生物, 线粒体膜电位, DNA片段分析, caspase, gambogic acid, GA3, antitumor, apoptosis, caspase, Bcl-2, cytochrome c
中文摘要：

Correspondence to Prof Wen-hu DUAN. E-mail：whduan@mail.shcnc.ac.cn Correspondence to Prof Jian DING,E-mail：jding@mail.shcnc.ac.cn

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期刊信息
  • 《中国药理学报：英文版》
  • 中国科技核心期刊
  • 主管单位:中国科学技术协会
  • 主办单位:中科院上海药物研究所
  • 主编：丁光生
  • 地址：上海市太原路294号31号楼
  • 邮编：200031
  • 邮箱：
  • 电话：021-54922821 54922822
  • 国际标准刊号：ISSN：1671-4083
  • 国内统一刊号：ISSN：31-1347/R
  • 邮发代号:4-295
  • 获奖情况:
  • 1992、1996年两届全国优秀科技期刊一等奖,1992、1996、1997年中国科协、中科院以及上海市优...,首届国家期刊奖、2000年中科院优秀期刊评比特别奖
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  • 被引量:1239