中文摘要：

卵巢开发是包含众多的基因的复杂进程。一个开发得好的卵巢是必要的让女性保留富饶并且复制后代。以便获得更好的卓见进与哺乳动物的卵巢开发的进程有关的分子的机制，我们在使用下一代的定序从婴儿和成年鼠标孤立的卵巢上执行了比较 transcriptomic 分析技术(固体) 。我们分别地在婴儿和成年舞台识别了 15,454 和 16,646 transcriptionally 活跃的基因。在这些基因之中，我们也鉴别 7021 差别表示了基因。我们的分析建议一般来说，成年卵巢有 transcriptomic 活动的高水平。然而，看来而为滤泡开发重要的基因的表示例如 Gdf9， Bmp4 和 Bmp15，是在成年人的 upregulated，与初发的滤泡开发有关的基因例如那些编码 Figla 和 Nobox，在婴儿卵巢是更活跃的。这些数据建议在基因表示的动态移动在卵巢开发和它期间是明显的这些变化工作便于滤泡成熟，另外的功能的基因什么时候学习，被考虑。而且，我们的调查也揭示了几条重要功能的小径，例如 apoptosis， MAPK 和类固醇生合成，看起来在与婴儿的那些相比的成年卵巢更活跃。这些调查结果将在老鼠和另外的哺乳动物和帮助在卵巢开发为未来研究提供一个稳固的基础扩展我们发生在出生后的卵巢开发期间的复杂分子、细胞的事件的理解。

英文摘要：

Ovary development is a complex process involving numerous genes. A well-developed ovary is essential for females to keep fertility and reproduce offspring. In order to gain a better insight into the molecular mechanisms related to the process of mammalian ovary development, we performed a comparative transcriptomic analysis on ovaries isolated from infant and adult mice by using next-generation sequencing technology （SOLID）. We identified 15,454 and 16,646 trans- criptionally active genes at the infant and adult stage, respectively. Among these genes, we also identified 7021 differentially expressed genes. Our analysis suggests that, in general, the adult ovary has a higher level of transcriptomic activity. However, it appears that genes related to primordial follicle development, such as those encoding Figla and Nobox, are more active in the infant ovary, whereas expression of genes vital for follicle development, such as Gdj~, Bmp4 and Bmpl5, is upreg- ulated in the adult. These data suggest a dynamic shift in gene expression during ovary development and it is apparent that these changes function to facilitate follicle maturation, when additional func- tional gene studies are considered. Furthermore, our investigation has also revealed several impor- tant functional pathways, such as apoptosis, MAPK and steroid biosynthesis, that appear to be much more active in the adult ovary compared to those of the infant. These findings will provide a solid foundation for future studies on ovary development in mice and other mammals and help to expand our understanding of the complex molecular and cellular events that occur during postnatal ovary development.