中文摘要：

目的 探讨成人喉部横纹肌肉瘤的临床表现、病理类型以及治疗和预后。方法 回顾性分析2003年7月~2015年10月北京同仁医院耳鼻咽喉头颈外科收治的5例成人横纹肌肉瘤患者临床及随访资料。结果 5例患者均以声音嘶哑为主诉,1例行手术治疗＋化疗＋放疗,2例手术治疗＋化疗,1例单纯行手术治疗,1例单纯化疗。病理类型：4例胚胎型,1例多形性。随访2例无瘤生存,3例死亡。结论成人喉部横纹肌肉瘤发病率低,治疗以手术切除联合化疗和放疗为主。预后与病理学分型以及肿瘤分期有关。

英文摘要：

OBJECTIVE To summarize the clinical features, diagnosis, treatment and prognosis of laryngeal rhabdomyosarcoma. METHODS The clinical data of 5 cases of adult laryngeal rhabdomyosarcoma treated in Beijing Tongren Hospital between 2003 and 2015 were analyzed retrospectively. RESULTS All the 5 cases firstly presented with hoarseness. 1 case was treated by combined therapy （surgery followed by radiotherapy and chemotherapy）. 2 patients received surgical treatment combined with chemotherapy. 1 patient received surgical treatment only. Another patient received chemotherapy only. Pathological type： 4 patients were embryonal rhabdomyosarcoma, 1 patient was pleomorphic rhabdomyosarcoma. In the follow-up of a period from 11 months to 8 years, 2 cases were alive without tumor, 3 patients were dead. CONCLUSION Adult laryngeal rhabdomyosarcoma is rare. Surgical resection combined with chemotherapy is the main treatment method, and the prognosis is related to the pathological type and tumor stage.