嗜酸粒细胞性中耳炎(eosinophilic otitis media,EOM)是一种少见的、难治的特殊类型中耳炎。其主要临床特点为中耳大量黄色粘稠分泌物,分泌物病理学和细胞学检查可见大量嗜酸粒细胞浸润。此类中耳炎患者常伴发支气管哮喘,一些患者同时患有鼻窦炎和(或)鼻息肉病;患者往往对常规中耳炎治疗措施效果欠佳。EOM比普通类型中耳炎对人类健康危害更大,少数患者可突然发生重度感音神经性耳聋,更易造成骨导听力损害等。在我国2012年中耳炎临床分类和手术分型指南中尚未提及。本文主要结合文献对EOM的临床特征、诊断及治疗进行较详细的描述,以期引起临床医师对此病的重视,早期对此类患者做出正确诊断和治疗,提高患者生活质量。
Eosinophilic otitis media(EOM)is a rare and refractory special type of otitis media. The main clinical features were a large amount of yellow thick secretions in the middle ear,and large amounts of eosinophilic infiltration were seen in pathology and cytology. Patients with this type of otitis media are often associated with bronchial asthma,while others suffer from sinusitis and/or nasal polyposis. Patients often have poor results by the routine method in treating with otitis media. EOM is more harmful to human health than the ordinary type of otitis media and more likely to cause damage to bone conduction hearing. A few patients can suffer from sudden sensorineural hearing loss. This disease has not been mentioned in the clinical classification and operation classification of otitis media in 2012 of China. In this paper,we discussed the pathogenesis,clinical features,diagnosis and management of EOM in detail,in order to attract clinicians to pay attention to this disease. Early diagnosis and treatment of such patients improve the quality of life of patients.