中文摘要：

气喘的发炎被一种类型调停 2 助手 T 房间(Th2 ) cytokine 反应，和堵住的 Th2 cytokine 生产被证明有一个有势力治疗学对气喘的发炎的效果。用 IL-4-green 荧光灯蛋白质(GFP ) 记者老鼠，我们表明了那 Bavachinin，从中国植物孤立的单个混合物，显著地禁止的 Th2 cytokine 生产包括 IL-4， IL-5 和 IL-13。尤其是，在 ovalbumin (卵) 的这复合几乎完全堵住的发炎敏化动物气喘模型。而且，我们证明这化学药品有选择地影响 GATA-3 的水平，由影响 GATA-3 mRNA 的稳定性最可能。第一次，我们的结果证明这单个混合物的潜在的治疗学的价值源于中国植物。

英文摘要：

Asthmatic inflammation is mediated by a type 2 helper T cell （Th2） cytokine response, and blocking Th2 cytokine production is proven to have a potent therapeutic effect against asthmatic inflammation. Using IL-4-green fluorescent protein （GFP） reporter mice, we demonstrated that Bavachinin, a single compound isolated from a Chinese herb, significantly inhibited Th2 cytokine production, including IL-4, IL-5 and IL-13. Notably, this compound almost completely blocked inflammation in the ovalbumin （OVA）-sensitized animal asthma model. Furthermore, we demonstrated that this chemical selectively affects the level of GATA-3, most likely by affecting the stability of GATA-3 mRNA. Our results demonstrate, for the first time, the potential therapeutic value of this single compound derived from Chinese herbs.