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Baculovirus vector-mediated transfer of NIS gene into colon tumor cells for radionuclide therapy
  • ISSN号：1007-9327
  • 期刊名称：《世界胃肠病学杂志：英文版》
  • 时间：0
  • 分类：R735.35[医药卫生—肿瘤;医药卫生—临床医学]
  • 作者机构：Shanghai Jiao Tong Univ, Dept Nucl Med, Ruijin Hosp, Sch Med, Shanghai 200025, Peoples R China
  • 相关基金：Supported by Grants from the National Natural Science Foundation of China,No.30570525;; the Shanghai Leading Academic Discipline Project,No.S30203
作者： Yin, Hong-Yan[1], Zhou, Xiang[1], Wu, Hai-Fei[1], Li, Biao[1], Zhang, Yi-Fan[1]
中文摘要：

AIM:To investigate the feasibility of radionuclide therapy of colon tumor cells by baculovirus vector-mediated transfer of the sodium/iodide symporter(NIS) gene.METHODS:A recombinant baculovirus plasmid carrying the NIS gene was constructed,and the viruses(BacNIS) were prepared using the Bac-to-Bac system.The infection efficiency in the colon cancer cell line SW1116 of a green fluorescent protein(GFP) expressing baculovirus(Bac-GFP) at different multiplicities of infection(MOI) with various concentrations o...

英文摘要：

AIM:To investigate the feasibility of radionuclide therapy of colon tumor cells by baculovirus vector-mediated transfer of the sodium/iodide symporter(NIS) gene.METHODS:A recombinant baculovirus plasmid carrying the NIS gene was constructed,and the viruses(BacNIS) were prepared using the Bac-to-Bac system.The infection efficiency in the colon cancer cell line SW1116 of a green fluorescent protein(GFP) expressing baculovirus(Bac-GFP) at different multiplicities of infection(MOI) with various concentrations o...

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期刊信息
  • 《世界胃肠病学杂志：英文版》
  • 主管单位:
  • 主办单位:百世登出版集团有限公司
  • 主编：
  • 地址：太原双塔西街77号
  • 邮编：100023
  • 邮箱：
  • 电话：0351-4078656
  • 国际标准刊号：ISSN：1007-9327
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  • 被引量:12408