中文摘要：

Wnt信号通路与血管发生有着密切联系,它能够通过使血管内皮细胞增殖、血管芽生、血管丛重塑、促进脉管系统成熟等多个阶段来诱导血管发生.通过动态变化的Wnt信号来改善如缺血性脑损伤等与内皮细胞密切相关的神经病理状况成为了近来研究的热点.本文就Wnt信号通路与血管发生之间的关系做一综述.

英文摘要：

Wnt signaling pathway is closely related to angiogenesis, which plays a crucial role in the vascular endothelial cell proliferation, and in the remodeling, sprouting and maturation of blood vessels. Detailed investigation on the Wnt signaling pathway might reveal potential new targets for the treatment of neural diseases. This review focused on the relationship between Wnt signaling pathway and angiogenesis.